Sleep apnea

de W. J. Randerath, B. M. Sanner, V. K. Somers, C. T. Bolliger, Felix J. F. Herth

Seeks to present the knowledge in the pathophysiology clinical presentation, diagnosis, and treatment of sleep apnea. Physiological approaches and modeling sleep and recent pathophysiologic findings in upper airway mechanics as well as the importance of inflammatory and oxidative processes and the underlying genetic aspects are discussed to open up avenues of investigation for better understanding and improved therapeutic options.