Microtubules

de Jeremy S. Hyams, Clive W. Lloyd

Microtubules play key roles in cell division, secretion, intracellular transport, morphogenesis, and ciliary and flagellar motion. Recent advances in microtubule research include molecular techniques that provide new insight into the tubulin dimer and its associated proteins, and video microscopy of microtubule assembly in vitro that has led to revision of concepts of microtubule dynamics and intracellular transport of organelles. Microtubules reflects the enormous and significant advances in microtubule research of the past decade. It provides up-to-date information on the art of microtubule research, building on the success of Dr. Hyams's 1979 landmark text. A distinguished group of editors and contributors presents reviews dealing with three central topics: the biochemistry and assembly of the tubulin dimer; associated proteins and regulation of microtubule function; and microtubule organization and function in the cell. Microtubules will prove invaluable for cell and developmental biologists working in this rapidly developing field.